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Press Release

POZEN Announces March 2 Webcast of Fourth Quarter and Year End Results

CHAPEL HILL, N.C.--(BUSINESS WIRE)--Feb. 16, 2006--POZEN Inc. (NASDAQ: POZN), announced today that it will release fourth quarter and year end results on March 2, 2006, before the market opens.

The announcement will be followed by a live webcast at 11:00 a.m. Eastern Time of a discussion by POZEN management of the earnings and business results. The webcast can be accessed on POZEN's website at www.pozen.com and will be archived and available for replay. The fourth quarter/year end earnings release can be accessed in the News section of POZEN's website.

POZEN is a pharmaceutical company committed to developing therapeutic advancements for diseases with unmet medical needs where it can improve efficacy, safety, and/or patient convenience. Since its inception, POZEN has focused its efforts primarily on the development of pharmaceutical products for the treatment of acute and chronic pain, migraine, and other pain-related conditions. POZEN has a development and commercialization alliance with GlaxoSmithKline. The company's common stock is traded on The Nasdaq Stock Market under the symbol "POZN". For detailed company information, including copies of this and other press releases, see POZEN's website: www.pozen.com.

CONTACT:
POZEN Inc.
Bill Hodges, Chief Financial Officer
919-913-1030
or
Fran Barsky, Director, Investor Relations
919-913-1044

SOURCE: POZEN Inc.