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Press Release

Pozen to Present at Piper Jaffray Health Care Conference

CHAPEL HILL, N.C.--(BUSINESS WIRE)--Jan. 20, 2005--POZEN, Inc. (NASDAQ: POZN) announced today that John R. Plachetka, Pharm.D., the company's chairman, president and chief executive officer, will be speaking to investors at the Piper Jaffray Health Care Conference on Thursday, January 27, 2005 at 3:30 p.m. Eastern Time in New York.

POZEN is a pharmaceutical company committed to developing therapeutic advancements for diseases with unmet medical needs where it can improve efficacy, safety, and/or patient convenience. Since its inception, POZEN has focused its efforts primarily on the development of pharmaceutical products for the treatment of migraine. POZEN is also exploring the development of product candidates in other pain-related therapeutic areas. POZEN has development and commercial alliances with GlaxoSmithKline, Xcel Pharmaceuticals, and Nycomed. The company's common stock is traded on The Nasdaq Stock Market under the symbol "POZN". For detailed company information, including copies of this and other press releases, see POZEN's website: www.pozen.com.

CONTACT:
POZEN, Inc.
Bill Hodges
919-913-1030
Fran Barsky
919-913-1044

SOURCE: POZEN, Inc.