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Press Release

POZEN CEO To Present at the Wells Fargo Securities Health Care Conference

CHAPEL HILL, N.C.--(BUSINESS WIRE)--March 18, 2004--POZEN Inc. (NASDAQ: POZN) announced today that John R. Plachetka, Pharm.D., the Company's chairman, president and chief executive officer, will be speaking to investors at the Wells Fargo Securities Health Care Conference on Wednesday, March 24, at 8:45 a.m. Eastern Time in New York City. Dr. Plachetka's presentation will be webcast live and archived on POZEN's home page at www.pozen.com.

POZEN is a pharmaceutical company developing therapeutic advancements in a cost effective manner. Product development efforts are focused on diseases with unmet medical needs where POZEN can improve efficacy, safety, and/or patient convenience. Since its inception, POZEN has developed the largest and most advanced product pipeline in the field of migraine. POZEN has development and commercial alliances with GlaxoSmithKline, Xcel Pharmaceuticals, and Nycomed. The company's common stock is traded on The Nasdaq Stock Market under the symbol "POZN". For detailed company information, including copies of this and other press releases, see POZEN's website: www.pozen.com.

Lisa Barthelemy, Director, Investor Relations,
John Barnhardt, Vice President, Finance and Administration,