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Press Release

POZEN Announces February 18 Webcast of Fourth Quarter and Full-Year 2003 Results

CHAPEL HILL, N.C., Feb 12, 2004 (BUSINESS WIRE) -- POZEN Inc. (NASDAQ:POZN), announced today that it will release fourth quarter and full-year 2003 results on February 18, 2004, before the market opens.

The announcement will be followed by a live webcast at 11:00 a.m. Eastern Time. POZEN management will discuss the earnings and business results. The webcast can be accessed on POZEN's website at www.pozen.com and will be archived and available for replay. The fourth quarter and full-year earnings release can be accessed in the News section of POZEN's website.

POZEN is a pharmaceutical company developing therapeutic advancements in a cost effective manner. Product development efforts are focused on diseases with unmet medical needs where POZEN can improve efficacy, safety, and/or patient convenience. Since its inception, POZEN has developed the largest and most advanced product pipeline in the field of migraine. POZEN has development and commercial alliances with GlaxoSmithKline, Xcel Pharmaceuticals, and Nycomed. The company's common stock is traded on The Nasdaq Stock Market under the symbol "POZN". For detailed company information, including copies of this and other press releases, see POZEN's website: www.pozen.com.

POZEN Inc.
Lisa Barthelemy
Director, Investor Relations
919-913-1044
or
John Barnhardt
VP, Finance & Administration
919-913-1030