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Press Release

Pozen Announces May 8 Webcast of First-Quarter Results

CHAPEL HILL, N.C., Apr 30, 2003 (BUSINESS WIRE) -- POZEN Inc. (NASDAQ: POZN), a pharmaceutical development company with a portfolio of product candidates for the treatment of migraine, today announced it will host a conference call following the release of financial results for the first quarter ended March 31, 2003. The company will release results before the market opens on Thursday, May 8, 2003. John R. Plachetka, Pharm.D., POZEN's chairman, president and chief executive officer, and Matthew E. Czajkowski, chief financial officer, will host the conference call the same day at 11:00 a.m. Eastern time.

The conference call will be simulcast live on the Internet and can be accessed by logging on to www.pozen.com. A replay will be available for seven days in the Investor Relations section of the company's website. POZEN's 1st quarter results release can be accessed in the News section of www.pozen.com and clicking on the release dated May 8, 2003.

POZEN is a pharmaceutical development company committed to building a portfolio of products with significant commercial potential in select therapeutic areas. POZEN's initial focus is on developing products for migraine therapy, a global market expected to exceed $3 billion this year. The company's common stock is traded on The Nasdaq Stock Market under the symbol "POZN."

CONTACT:
POZEN Inc.
Matt Czajkowski
Chief Financial Officer
919-913-1030
or
Lisa Barthelemy
Director, Investor Relations
919-913-1044